Academic Leader


Rev. Dr Lehlohonolo J. Mathibe is registered with the South African Pharmacy Council (SAPC) as a pharmacist. In addition to a B.Pharm degree (obtained from the University of the North, now called University of Limpopo), he holds master’s degree in clinical pharmacology (M.ClinPharm) from the University of Natal (now called the University of KwaZulu-Natal, UKZN), master’s degree (MSc) in evidence-based healthcare from the University of Oxford, England and a doctorate (PhD) from UKZN. He started working as a lecturer in the Department of Experimental & Clinical Pharmacology, Nelson R. Mandela School of Medicine, University of Natal in 2001.

Since then, he has supervised postgraduate research projects and delivered pharmacology lectures to nursing, medical, optometry, dental therapy, pharmacy and nutrition students who pursued their studies with UKZN. At UKZN – he is a member of the College of Health Science’s Transformation Committee; at School (Faculty) level), he is a member of Research Ethics and Higher Degrees Committee (REHDC); and a research coordinator for the Discipline of Pharmaceutical Sciences (DoPS 2020/21). At Provincial level, he currently (2020 – 2022) serves in the KZN Provincial Pharmacy and Therapeutics Committee (PTC) which advises the MEC for Health in KZN on rational use of medicines. Nationally, Revd. Dr Mathibe is a current (2021/22) member of the Expert Working Committee of the South African Health Products Regulatory Authority (SAHPRA). This committee was tasked with formulation of a legal framework for control and commercialisation of traditional medicines in South Africa.

His main research interests include laboratory-based and clinical work in pharmaco-economics, pharmacovigilance, evidence-based medicine, breast cancer and investigation on pure compounds isolated from indigenous southern African medicinal plants. His research findings have been published in national and international peer-reviewed journals. 

List of Publications

Recent Publications (2015 – 2020)

  1. Mathibe LJ, Zwane NP. Unnecessary antimicrobial prescribing for upper respiratory tract infections in children in Pietermaritzburg, South Africa. African Health Sciences 2020, 20(3); 1133-1142.
  2. Tlhakudi P, Mathibe L.J. Management of stable angina pectoris in private healthcare settings in South Africa. CardioVascular Journal of Africa 29 (4); 237-240. Awarded 1st Prize, as the South African Society for Basic and Clinical Pharmacology (SASBCP) Best Publication 2018 (clinical pharmacology category), at the 53rd Annual SASBCP Conference held in Pretoria, South Africa from 5th – 7th October 2019.
  3. Mathibe LJ, Botha J, Naidoo S. Effects of Z-venusol, Isolated from Gunnera perpensa, on IL-6 and cAMP Activity in Human Breast Cancer Cells In VitroSouth African Journal of Botany 108; 96-99.
  4. Mathibe LJ, Botha JH, Naidoo S. Z-venusol, from Gunnera perpensa, Induces Apoptotic Cell Death in Breast Cancer Cells In VitroSouth African Journal of Botany 102; 228-233
  5. Mathibe LJ. The Strength of Gunnera perpensa’s “Evidence of Traditional Use”. South African Family Practice 58(S1): S39–S40 
  6. Mathibe LJ. Implications of Methodist Clergies’ Average Life Span and Missional Lessons Learned from Obituaries of Deceased Ministers. HTS Teologiese Studies/ Theological Studies 2015, 71 (3).