Dr Bahareh Honarparvar
Person | Dr Bahareh Honarparvar | |
Telephone | 031-2608482 | |
Honarparvar@ukzn.ac.za | ||
Campus | Westville | |
Research Interests | Computational Chemistry | |
Designation | Honorary Lecturer
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Biosketch | Dr. Bahareh Honarparvar received her Ph.D. degree in Physical Chemistry
(Computational Chemistry) from Iran in 2010. Her Ph.D thesis was about the application of ab initio electronic structure calculations for drug-like compounds. From 2002 up to 2006, she was manager of industrial projects in Ministry of oil as well as Polymer and petrochemical research Centre in Tehran-Iran. In 2007, she was employed as a project manager and educational research member in Institution for Curriculum Development & Educational Innovations, Tehran, Iran till April 2010. After getting her PhD, she started her research on computational HIV drug design as a computational postdoctoral fellow at KwaZulu-Natal University in Durban, South Africa from July 2010 up to June 2013. She is currently appointed as a lecturer in the school of Health Sciences (Pharmaceutical Sciences). Her research interest is mainly on applying computational medicinal chemistry approaches (Molecular Dynamic simulation, molecular docking, binding free energy calculation) to investigate enzyme-inhibitor interactions for synthesizing novel drugs related to different diseases.
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List of Publications | Proline N-oxides: modulators of the 3D conformation of linear peptides through “NO-turns”. Farahani MD, Honarparvar B, Albericio F, Maguire GE, Govender T, Arvidsson PI, Kruger HG. Org Biomol Chem. 2014 Jul 7;12(25):4479-90. doi: 10.1039/c4ob00433g. PMID: 24849849
Honarparvar B, Govender T, Maguire GE, Soliman ME, Kruger HG. Chem Rev. 2014 Jan 8;114(1):493-537. doi: 10.1021/cr300314q. Epub 2013 Sep 11. No abstract available. PMID: 24024775
Makatini MM, Petzold K, Arvidsson PI, Honarparvar B, Govender T, Maguire GE, Parboosing R, Sayed Y, Soliman ME, Kruger HG. Eur J Med Chem. 2012 Nov;57:459-67. doi: 10.1016/j.ejmech.2012.06.019. Epub 2012 Jul 16. PMID: 22867528
Honarparvar B, Makatini MM, Pawar SA, Petzold K, Soliman ME, Arvidsson PI, Sayed Y, Govender T, Maguire GE, Kruger HG. ChemMedChem. 2012 Jun;7(6):1009-19. doi: 10.1002/cmdc.201100512. Epub 2012 Apr 27. PMID: 22544389
Makatini MM, Petzold K, Alves CN, Arvidsson PI, Honarparvar B, Govender P, Govender T, Kruger HG, Sayed Y, JerônimoLameira, Maguire GE, Soliman ME. J Enzyme Inhib Med Chem. 2013 Feb;28(1):78-88. doi: 10.3109/14756366.2011.633907. Epub 2012 Feb 17. PMID: 22339087
Makatini MM, Petzold K, Sriharsha SN, Ndlovu N, Soliman ME, Honarparvar B, Parboosing R, Naidoo A, Arvidsson PI, Sayed Y, Govender P, Maguire GE, Kruger HG, Govender T. Eur J Med Chem. 2011 Sep;46(9):3976-85. doi: 10.1016/j.ejmech.2011.05.071. Epub 2011 Jun 7. PMID:21741133
Irani S, Monajjemi M, Honarparvar B, Atyabi S, Sadeghizadeh M. Int J Nanomedicine. 2011;6:213-8. doi: 10.2147/IJN.S14632. Epub 2011 Jan 25. PMID: 21499418
Pentacycloundecane-based inhibitors of wild-type C-South African HIV-protease. Makatini MM, Petzold K, Sriharsha SN, Soliman ME, Honarparvar B, Arvidsson PI, Sayed Y, Govender P, Maguire GE, Kruger HG, Govender T. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2274-7. doi: 10.1016/j.bmcl.2011.02.105. Epub 2011 Mar 1. PMID: 21429747
KY, Mercader AG, Saavedra LM, Honarparvar B, Romanelli GP, Duchowicz PR. (2014) QSAR analysis on tacrine-related acetylcholinesterase inhibitors. Journal of biomedical science.21: 84-90, doi:10.1186/s12929-014-0084-0.
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